Ishikawa Hisanori served as a bushō in Bitchū Province during the Sengoku period.
In 1567, Hisanori became head of the family after the death from illness of his father, Ishikawa Hisatomo, related to injuries sustained at the Battle of Myōzenji against Ukita Naoie. In 1571, while Hisanori participated in the Kyūshū Pacification on the side of Mōri Motonari, his base at Kōzan Caste in Bitchū was captured by forces led by Amago Katsuhisa. He then recovered the castle. In 1574, after Mimura Motochika separated from the forces of Mōri Terumoto and sided with Oda Nobunaga, Hisanori followed Motochika. In 1575, at the Battle of Bitchū-Matsuyama Castle, Hisanori served as second-in-command to Motochika and succeeded in entering the castle, but lost the battle and took his own life.