Ike Yorikazu served as a bushō during the Sengoku and Azuchi-Momoyama periods. He was a retainer of the Chōsokabe clan and served as the lord of Ike Castle in the Nagaoka District of Tosa Province in Shikoku.
Yorikazu was born as the son of Ike Yorisada, the second son of Hosokawa Teisuke of the Tōchi-Hosokawa clan. The Tōchi-Hosokawa were members of the Hosokawa clan descended from Hosokawa Yoshitoshi, a bushi from the Kamakura period.
The Tosa-Ike clan were kokujin, or provincial landowners, with landholdings in Tanezaki along the eastern part of Tosa Bay. Yorikazu disputed with Chōsokabe Kunichika, but eventuallly submitted and wed Kunichika’s daughter. After coming under the command of the Chōsokabe,Yorikazu served in the main division of the Chōsokabe naval forces, generating revenues for the family by engaging in trade with counterparts in Sakai. Later, he had a falling out with his wife and was suspected of conspiring to rebel for which Chōsokabe Motochika ordered him to take his own life.