Ichikuri Hōgyū served as a bushō and retainer of the Ōsaki clan, and as lord of Ichikuri Castle in Dewa Province during the Sengoku and Azuchi-Momoyama periods.
In 1590, Hōgyū joined his grandson, Ichikuri Takaharu, in an uprising against the new lords in their territory. In an event known as the Kasai-Ōsaki Uprising (Kasai-Ōsaki ikki), former retainers of the Kasai and Ōsaki clans protested the dismissal and replacement of these clans with the Kimura clan. Kimura Yoshikiyo and his son, Kimura Kiyohisa, were assigned control of the territory as part of Toyotomi Hideyoshi’s effort to garner control of the northern provinces in a campaign launched in the summer of 1590 known as the Ōshū Retribution (Ōshū shioki). Upon the outbreak of the uprising, Yoshikiyo and Kiyohisa sought refuge in Sanuma Castle in Mutsu Province, and were rescued by Date Masamune. After Masamune was summoned to Kyōto, Hōgyū and Takaharu, together with their followers, took over Sanuma Castle and made a spirited defense against an assault by Masamune. Outnumbered, Hōgyū enabled Takaharu to safely escape and then made a last stand in the castle, perishing at the age of ninety-two.