Amano Yasumune lived in the Azuchi-Momoyama and Edo periods.  He inherited the domain with Kōkokuji Castle in Suruga from his father, Amano Yasukage.  His mother was the daughter of Ushida Yukimasa, a retainer of Oda Nobunaga. He was married to the daughter of Anbe Nobukatsu, a retainer of the Imagawa and, later, the Tokugawa clan.

His father, Yasukage, was a close associate of Tokugawa Ieyasu.  Yasukage was known as one of the Mikawa sanbugyō, or Three Magistrates of Mikawa, along with Honda Shigetsugu and Kōriki Kiyonaga.  After Ieyasu moved to the Kantō Region, Yasukage received a domain of 3,000 koku in Shimōsa Province, and assigned the role of a machi-bugyō in Edo, as an official administrator of the municipal areas of the territory.  In 1601, he further expanded holdings with 10,000 koku as lord of the domain for Kōkokuji Castle. In 1607, after Yasukage had a falling out with Honda Masazumi, Yasumune obeyed his father and fled, after which their territory was seized.  In 1628, Yasumune was pardoned, received 1000 bales of rice, and served as a hatamoto for the Tokugawa bakufu.