Shimotsuma Raikei served as a bushō and bōkan, or head of administrative affairs, for the Hongan Temple during the Sengoku period.

Raikei was born as the second son of Shimotsuma Raizen and younger brother of Raigen.  He was the father of Mitsuyori, Shinrai, and Yūkei.  Raikei was commonly known as Genshirō.

Raikei served Jitsunyo, the ninth high priest of the Hongan Temple.  In 1506, monks from Settsu and Kawachi provinces backed Jikken (the younger brother of Jitsunyo of a different mother) as a replacement for Jitsunyo in an incident known as the Kawachi Disturbance.  Upon orders of Jitsunyo, Raikei apprehended Jikken, Jitsujun and Jitsujū.  Jitsunyo then ordered Raikei to support Jitsunyo’s grandson, Shōnyo, as the tenth high priest.  In the course of the Kyōroku-Tenbun Conflict, discord arose between Raikei and his nephews, Shimotsuma Raishū and Shimotsuma Raisei, after which he left the Hongan Temple.  In 1535, Shōnyo reconciled with Hosokawa Harumoto.  As members of the war faction, Raishū and Raisei were removed from their positions and Raikei returned to the service of the Hongan Temple.  Raikei headed toward Harumoto as a messenger of peace and worked to suppress riots by monks in bakufu territory and engage in diplomacy with assorted daimyō.

Raikei died in 1541 and was succeeded by his eldest son, Mitsuyori.