Ii Naomune served as a bushō during the Sengoku period.  He was a retainer of the Imagawa clan.

Naomune was born as the lineal heir of Ii Naohira, the lord of Iinoya Castle in the Inasa District of Tōtōmi Province.  The Ii were a kokujin, or provincial landowner, in Tōtōmi serving from the generation of Naohira as retainers of the Imagawa clan.  Naohira transferred headship of the clan to Naomune but, on 1/29 of Tenbun 11 (1542), he obeyed Imagawa Yoshimoto by serving in the assault on Tahara Castle in Mikawa Province and was killed in action.  He was succeeded by his son, Ii Naomori.

Naomune’s wife, Jōshinin, built the Nyoi Temple to pray for his soul.

The reference to 1542 as the year of Naomune’s demise is based on a genealogical record but the Imagawa did not attack Tahara Castle in 1542.  The invasion of Mikawa by the Imagawa occurred from the latter half of 1546 so questions regarding his demise remain.  According to other genealogies, his died in the first month of 1551 or in 1554.  One scholar noted that 1542 may have been a mistranslation and there is a strong likelihood that he was killed at Tahara Castle in 1547.

In historical records, there is almost no information regarding the achievements of Naomune.  Based on evidence that his son, Naomori, engaged in acts typical of a lord including the issuance of documents from 1539 while the age difference between Naohira and Naomori was seventeen years which raises doubts regarding the existence of Naomune.

According to another scholar, there are no traces of Naomune or Ii Naochika in sources from the period and first appear in genealogies that were created in later eras so their existence remains in question.