Hironaka Takasuke served as a bushō during the Sengoku period.  He was a retainer of the Ōuchi clan.

Takasuke was born as the son of Hironaka Takakane, a senior retainer of the Ōuchi clan and deputy military governor of Aki.

In 1555, at the Battle of Itsukushima, he followed his father and sailed into battle against the army of Mōri Motonari but, together with his father, was killed in action.